Techniques séparatives

À la pointe des sciences de la séparation miniaturisées depuis vingt ans, l’équipe Techsep innove quotidiennement pour apporter des solutions originales à des problèmes analytiques de plus en plus complexes. L’expertise unique de l’équipe en France dans la synthèse de phases stationnaires monolithiques en format miniaturisé lui permet d’explorer de nouvelles pistes analytiques à la fois en liquide (Nano LC, techniques électrocinétiques) et en chromatographie gazeuse. En plus de son expertise dans les méthodes de séparation miniaturisées et leur couplage à différents modes de détection, cette compétence unique dans la conception de matériaux dédiés donne à l’équipe une approche analytique globale concernant les outils miniaturisés intégrés et même automatisés.

Axes de recherche

Chromatographie en phase gazeuse à haute performance (HPGC) basée sur l’utilisation de petites colonnes capillaires remplies adaptées aux applications industrielles à fort potentiel. L’utilisation d’une colonne remplie dans un système de chromatographie en phase gazeuse modifié permet d’appliquer une pression de gaz porteur pouvant atteindre 60 bars. Ces systèmes évitent les problèmes de décompression lors de l’injection et limitent ainsi tout changement dans la composition relative de l’échantillon.
Caractérisation des interactions protéine/métal. Application à la vectorisation et à la surveillance des médicaments (composés métalliques à des fins thérapeutiques et/ou diagnostiques) et au diagnostic de la toxicité des métaux endogènes (maladies neurodégénératives).
Characterization of Membrane Protein / Ligand Interactions. Application to Fragment-based drug discovery (FBDD).

Personnels

  • Chercheurs et enseignants-chercheurs

    • Claire DEMESMAY
    • Vincent DUGAS
    • Agnès HAGEGE
    • Jérome RANDON
    • Frédéric JEANROY
  • Soutien à la recherche

    • Julie GIL
    • Rami LAOUFI
  • Doctorants

    • Adrien DELOCHE
    • Michel RACHKIDI
    • François-Xavier VIDAL
  • Autres

    • Yasmine SOUKI

Publications (sources HAL)

Articles dans une revue

  • Frédéric Jeanroy, Claire Demesmay, Vincent Dugas. Contribution of separation sciences to the deciphering of the binding sites of glycosaminoglycans to proteins. Separation and Purification Reviews, In press, ?10.1080/15422119.2023.2293027?. ?hal-04579046?
  • Léna Carmès, Guillaume Bort, François Lux, Léa Seban, Paul Rocchi, et al.. AGuIX nanoparticle-nanobody bioconjugates to target immune checkpoint receptors. Nanoscale, 2024, ?10.1039/D3NR04777F?. ?hal-04370969?
  • Pierre Lanteri, yohann clement, Jérôme Randon. Une situation pédagogique sur microcontrôleur pour faire émerger les besoins en analyse de données - le tri des matières plastiques. L'Actualité Chimique, 2023, 487, pp.37. ?hal-04240537?
  • Thomas Alexandre Brunet, Sophie Ayciriex, Delphine Arquier, Jérôme Lemoine, Jérôme Randon, et al.. Scout triggered multiple reaction monitoring mass spectrometry for the rapid transfer of large multiplexed targeted methods in metabolomics.. Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2023, 1228, pp.123849. ?10.1016/j.jchromb.2023.123849?. ?hal-04216213?
  • Michel Rachkidi, Laura Alonso-Sobrado, Guy Raffin, Eric Colinet, Jérôme Randon. Dual detection chromatographic method for fast characterization of nano-gravimetric detector. Talanta, 2023, 257, pp.124359. ?10.1016/j.talanta.2023.124359?. ?hal-04204916?
  • Jean-Louis Banères, Thomas Botzanowski, Jean A Boutin, Barbara Calamini, Jérôme Castel, et al.. Biophysical Dissection of Isolated GPCRs: The Adenosine A2A Receptor under the Bistouries. Receptors and Channels, 2023, 2 (1), pp.47-92. ?10.3390/receptors2010004?. ?hal-04003751?
  • Jérôme Randon. La vidéo pour s’engager dans la démarche scientifique. L'Actualité Chimique, 2023, 481, pp.39. ?hal-04240580?
  • Julie Gil, Gaëtan Passalacqua, Adrien Deloche, François-Xavier Vidal, Vincent Dugas, et al.. Optimization of the Preparation of Hydrophilic Poly(DHPMA-co-MBA) Monolithic Capillary Columns: A New Support for Affinity Chromatography. Separations, 2023, 10 (8), pp.437. ?10.3390/separations10080437?. ?hal-04184396?
  • Jérôme Randon, Vincent Dugas, Claire Demesmay. Reduce cognitive overload with systemic cause-effect relation maps to teach and learn chromatography. Analytical and Bioanalytical Chemistry, 2023, 415 (20), pp.4839-4847. ?10.1007/s00216-023-04804-6?. ?hal-04184383?
  • Frédéric Jeanroy, Clothilde Comby-Zerbino, Claire Demesmay, Vincent Dugas. Miniaturized affinity chromatography: A powerful technique for the isolation of high affinity GAGs sequences prior to their identification by MALDI-TOF MS. Analytica Chimica Acta, 2023, 1277, pp.341656. ?10.1016/j.aca.2023.341656?. ?hal-04184392?
  • Needa Brown, Paul Rocchi, Léna Carmès, Romy Guthier, Meghna Iyer, et al.. Tuning ultrasmall theranostic nanoparticles for MRI contrast and radiation dose amplification. Theranostics, 2023, 13, pp.4711 - 4729. ?10.7150/thno.85663?. ?hal-04222633?
  • Yoan Monneau, Cyrielle Arrault, Coraline Duroux, Marie Martin, Fabien Chirot, et al.. Structural and dynamical insights into SilE silver binding from combined analytical probes. Physical Chemistry Chemical Physics, 2023, 25 (4), pp.3061-3071. ?10.1039/D2CP04206A?. ?hal-03960103?
  • Julie GIL, Isabelle Krimm, Vincent Dugas, Claire Demesmay. Preparation of miniaturized hydrophilic affinity monoliths: Towards a reduction of non-specific interactions and an increased target protein density. Journal of Chromatography A, 2023, 1687, pp.463670. ?10.1016/j.chroma.2022.463670?. ?hal-03888930?
  • Frédéric Jeanroy, Fanny Demontrond, François-Xavier Vidal, David Gueyrard, Sébastien Vidal, et al.. Deciphering dynamic combinatorial libraries of glycoclusters with miniaturized weak affinity chromatography coupled with mass spectrometry (nano-FAC-MS). Analytica Chimica Acta, 2023, 1261, pp.341227. ?10.1016/j.aca.2023.341227?. ?hal-04092385?
  • Adrien Deloche, François-Xavier Vidal, Lucile Jammas, Renaud Wagner, Vincent Dugas, et al.. Extending the Affinity Range of Weak Affinity Chromatography for The Identification of Weak Ligands Targeting Membrane Proteins. Molecules, 2023, 28 (20), pp.7113. ?10.3390/molecules28207113?. ?hal-04262371?
  • Jérôme Randon, Vincent Dugas, Claire Demesmay. Mettre de l’ordre dans les espèces. L'Actualité Chimique, 2022, 475, pp.48-53. ?hal-03975751?
  • Frédéric Jeanroy, Claire Demesmay, Vincent Dugas. Miniaturized antithrombin III affinity monolithic columns coupled to TOF-MS for the selective capture and release of fondaparinux a high affinity antithrombin III ligand. Talanta, 2022, 241, pp.123275. ?10.1016/j.talanta.2022.123275?. ?hal-03615552?
  • Coraline Duroux, Agnès Hagège. CE-ICP-MS to probe Aβ1-42/copper (II) interactions, a complementary tool to study amyloid aggregation in Alzheimer's disease. Metallomics, 2022, 14 (1), ?10.1093/mtomcs/mfab075?. ?hal-03602774?
  • Arthur Degasperi, Lucie Labied, Carole Farre, Emmanuel Moreau, Matteo Martini, et al.. Probing the protein corona of gold/silica nanoparticles by Taylor dispersion analysis-ICP-MS. Talanta, 2022, 243, pp.123386. ?10.1016/j.talanta.2022.123386?. ?hal-03663936?
  • Paul Rocchi, Lucie Labied, Tristan Doussineau, Michel Julien, Barbara Giroud, et al.. Identification of Molecular Fragments in Equilibrium with Polysiloxane Ultrasmall Nanoparticles. Nanomaterials, 2022, 12 (5), pp.738. ?10.3390/nano12050738?. ?hal-03593216?
  • Jérôme Randon, Vincent Dugas, Claire Demesmay. Le bon sens de la chromatographie en phase liquide. L'Actualité Chimique, 2022, 469, pp.36-40. ?hal-03975763?
  • Renaud Passieux, Guillaume Sudre, Alexandra Montembault, Martine Renard, Agnès Hagege, et al.. Cytocompatibility / Antibacterial Activity Trade-off for Knittable Wet-Spun Chitosan Monofilaments Functionalized by the In Situ Incorporation of Cu 2+ and Zn 2+. ACS Biomaterials Science and Engineering, 2022, pp.acsbiomaterials.2c00079. ?10.1021/acsbiomaterials.2c00079?. ?hal-03593148?
  • Coraline Duroux, Agnès Hagège. Interactions between copper (II) and β-amyloid peptide using capillary electrophoresis–ICP–MS: Kd measurements at the nanogram scale. Analytical and Bioanalytical Chemistry, 2022, ?10.1007/s00216-021-03769-8?. ?hal-03443367?
  • Andrea Gottardini, Claude Netter, Vincent Dugas, Claire Demesmay. Two Original Experimental Setups for Staircase Frontal Affinity Chromatography at the Miniaturized Scale. Analytical Chemistry, 2021, 93 (51), pp.16981-16986. ?10.1021/acs.analchem.1c04772?. ?hal-03507849?
  • Linda Ayouni-Derouiche, Frédérique Barbier-Bessueille, Nicole Gilon, Agnès Hagège. Analyse de traces et d’ultra-traces d’éléments. Les Techniques de l'Ingenieur, 2021, pp.P3860 V4. ?10.51257/a-v4-p3860?. ?hal-03508164?
  • Andrea Gottardini, Vincent Dugas, Claire Demesmay. Development of a multi-layering protein grafting process on miniaturized monolithic columns for weak affinity nano liquid chromatography application purposes. Journal of Chromatography A, 2021, 1657, pp.462567. ?10.1016/j.chroma.2021.462567?. ?hal-03508515?
  • Jonathan Piard, Jérôme Randon. L'absorbance : comment rendre sa compréhension plus lumineuse aux yeux des apprenant•es. Le Bulletin de l'Union des Professeurs de Physique et de Chimie, 2021. ?hal-03929595?
  • Huian Liu, Jérôme Randon. Behavior of micro pillar array column in high pressure gas chromatography.. Journal of Chromatography A, 2021, 1656, pp.462551. ?10.1016/j.chroma.2021.462551?. ?hal-03356055?
  • Jérôme Randon, Xavier Bataille. Enquête à la maison : calorimétrie et contrôle qualité. L'Actualité Chimique, 2021, 463, pp.45. ?hal-03975779?
  • Tatiana Gritsaenko, Valérie Pierrefite-Carle, Gaëlle Creff, Bastien Simoneau, Agnès Hagège, et al.. Low doses of uranium and osteoclastic bone resorption: key reciprocal effects evidenced using new in vitro biomimetic models of bone matrix. Archives of Toxicology, 2021, 95 (3), pp.1023-1037. ?10.1007/s00204-020-02966-1?. ?hal-03108237?
  • Lucie Labied, Paul Rocchi, Tristan Doussineau, Jérôme Randon, Olivier Tillement, et al.. Biodegradation of metal-based ultra-small nanoparticles: A combined approach using TDA-ICP-MS and CE-ICP-MS. Analytica Chimica Acta, 2021, 1185, pp.339081. ?10.1016/j.aca.2021.339081?. ?hal-03352486?
  • Lucie Labied, Paul Rocchi, Tristan Doussineau, Jérôme Randon, Olivier Tillement, et al.. Taylor dispersion analysis coupled to ICP-MS for ultrasmall nano-particle size measurement: from drug product to biological media studies. Analytical Chemistry, 2021, 93 (3), pp.1254-1259. ?10.1021/acs.analchem.0c03988?. ?hal-03093902?
  • Caroline Bourgeois, Nicolas Blanc, Jean-Claude Cannot, Claire Demesmay. Towards a Non-Biased Formaldehyde Quantification in Leather: New Derivatization Conditions before HPLC Analysis of 2,4-Dinitrophenylhydrazine Derivatives. Molecules, 2020, 25 (23), pp.5765. ?10.3390/molecules25235765?. ?hal-03093760?
  • Lucile Lecas, Lucie Hartmann, Lydia Caro, Sarah Mohamed-Bouteben, Claire Raingeval, et al.. Miniaturized weak affinity chromatography for ligand identification of nanodiscs-embedded G-protein coupled receptors. Analytica Chimica Acta, 2020, 1113, pp.26-35. ?10.1016/j.aca.2020.03.062?. ?hal-03045118?
  • Léna Jaravel, Baptiste Schindler, Jérôme Randon, Isabelle Compagnon, Claire Demesmay, et al.. Off-line coupling of capillary isotachophoresis separation to IRMPD spectroscopy for glycosaminoglycans analysis: Application to the chondroitin sulfate disaccharides model solutes. Journal of Chromatography A, 2020, 1617, pp.460782. ?10.1016/j.chroma.2019.460782?. ?hal-02448330?
  • Laura Alonso Sobrado, Matthieu Loriau, Serge Junca, Christophe Tremaudant, Pierre Puget, et al.. Characterization of Nano-Gravimetric-Detector Response and Application to Petroleum Fluids up to C 34. Analytical Chemistry, In press, Epub 2020 Nov 24. ?10.1021/acs.analchem.0c03157?. ?hal-03049156?
  • Lucile Lecas, Vincent Dugas, Claire Demesmay. Affinity Chromatography: A Powerful Tool in Drug Discovery for Investigating Ligand/membrane Protein Interactions. Separation and Purification Reviews, 2020, pp.1-18. ?10.1080/15422119.2020.1749852?. ?hal-02566413?
  • Isabelle George, Chiara Uboldi, Elodie Bernard, Marcos Sanles Sobrido, Sarah Dine, et al.. Toxicological Assessment of ITER-Like Tungsten Nanoparticles Using an In Vitro 3D Human Airway Epithelium Model. Nanomaterials, 2019, 9 (10), pp.1374. ?10.3390/nano9101374?. ?cea-02302666?
  • Ivo Leito, Anu Teearu, Johan Bobacka, Jérôme Randon, Jonas Bergquist. EACH (Excellence in Analytical Chemistry), an Erasmus Mundus Joint Programme: progress and success. Analytical and Bioanalytical Chemistry, 2019, 411 (23), pp.5913-5921. ?10.1007/s00216-019-01988-8?. ?hal-02437218?
  • Lucile Hurault, Gaëlle Creff, Agnès Hagège, Sabine Santucci-Darmanin, Sophie Pagnotta, et al.. Uranium Effect on Osteocytic Cells In Vitro. Toxicological Sciences, 2019, 170 (1), pp.199-209. ?10.1093/toxsci/kfz087?. ?hal-02333849?
  • Huian Liu, Guy Raffin, Guillaume Trutt, Vincent Dugas, Claire Demesmay, et al.. Hyphenation of short monolithic silica capillary column with vacuum ultraviolet spectroscopy detector for light hydrocarbons separation. Journal of Chromatography A, 2019, 1595, pp.174-179. ?10.1016/j.chroma.2019.02.033?. ?hal-02109278?
  • José Néri-Quiroz, Fabrice Canto, Laurent Guillerme, Laurent Couston, Alastair Magnaldo, et al.. Microfluidic ballistic regime for the generation of linear gradients inside a capillary column: Proof-of-concept and application to the miniaturized acid-base volumetric titration. Talanta, 2019, 196, pp.237-242. ?10.1016/j.talanta.2018.12.045?. ?hal-02109272?
  • Mathilde Fontaine, Yohann Clément, Nicolas Blanc, Claire Demesmay. Hexavalent chromium release from leather over time natural ageing vs accelerated ageing according to a multivariate approach. Journal of Hazardous Materials, 2019, 368, pp.811-818. ?10.1016/j.jhazmat.2018.12.112?. ?hal-02076711?
  • Lucile Lecas, Jérôme Randon, Alain Berthod, Vincent Dugas, Claire Demesmay. Monolith weak affinity chromatography for μg-protein-ligand interaction study. Journal of Pharmaceutical and Biomedical Analysis, 2019, 166, pp.164-173. ?10.1016/j.jpba.2019.01.012?. ?hal-02015987?
  • Maria Betzabeth Espina-Benitez, Jérôme Randon, Claire Demesmay, Vincent Dugas. Development of a new in-line coupling of a miniaturized boronate affinity monolithic column with reversed-phase silica monolithic capillary column for analysis of cis-diol-containing nucleoside compounds. Journal of Chromatography A, 2019, 1597, pp.209-213. ?10.1016/j.chroma.2019.04.002?. ?hal-02109114?
  • Maria Betzabeth Espina-Benitez, Fabienne Marconi, Jérôme Randon, Claire Demesmay, Vincent Dugas. Evaluation of boronate affinity solid-phase extraction coupled in-line to capillary isoelectric focusing for the analysis of catecholamines in urine. Analytica Chimica Acta, 2018, 1034, pp.195-203. ?10.1016/j.aca.2018.06.017?. ?hal-01900239?
  • Baptiste Schindler, Gabrielle Laloy-Borgna, Loic Barnes, Abdul-Rahman Allouche, Elodie Bouju, et al.. Online Separation and Identification of Isomers Using Infrared Multiple Photon Dissociation Ion Spectroscopy Coupled to Liquid Chromatography: Application to the Analysis of Disaccharides Regio-Isomers and Monosaccharide Anomers. Analytical Chemistry, 2018, 90 (20), pp.11741-11745. ?10.1021/acs.analchem.8b02801?. ?hal-01936856?
  • Alexis Martin, Christelle Margoum, Antoine Jolivet, Azziz Assoumani, Bachir El Moujahid, et al.. Calibration of silicone rubber rods as passive samplers for pesticides at two different flow velocities: Modeling of sampling rates under water boundary layer and polymer control. Environmental Toxicology and Chemistry, 2018, 37 (4), pp.1208-1218. ?10.1002/etc.4050?. ?hal-01803608?
  • Nicolas A.O. Morin, Nicolas Mazzella, Hans Peter H. Arp, Jérôme Randon, Julien Camilleri, et al.. Kinetic accumulation processes and models for 43 micropollutants in “pharmaceutical” POCIS. Science of the Total Environment, 2018, 615, pp.197-207. ?10.1016/j.scitotenv.2017.08.311?. ?hal-02119712?
  • Maria Betzabeth Espina-Benitez, Jérôme Randon, Claire Demesmay, Vincent Dugas. Back to BAC: Insights into Boronate Affinity Chromatography Interaction Mechanisms. Separation and Purification Reviews, 2018, 47 (3), pp.214-228. ?10.1080/15422119.2017.1365085?. ?hal-01803321?
  • Meriem Zouari, Laurence Bois, Vincent Dugas, Souhaira Hbaieb, Yves Chevalier, et al.. Monolith Passive Adsorbers Prepared with Hydrophobic Porous Silica Rods Coated with Hydrogel. Analytical Letters, 2017, 51 (6), pp.935-954. ?10.1080/00032719.2017.1365368?. ?hal-02139832?
  • Huian Liu, Guy Raffin, Guillaume Trutt, Jérôme Randon. Is vacuum ultraviolet detector a concentration or a mass dependent detector?. Journal of Chromatography A, 2017, 1530, pp.171-175. ?10.1016/j.chroma.2017.11.028?. ?hal-01646649?
  • Mathilde Fontaine, Nicolas Blanc, Jean-Claude Cannot, Claire Demesmay. Ion Chromatography with Post Column Derivatization for the Determination of Hexavalent Chromium in Dyed Leather. Influence of the Preparation Method and of the Sampling Location . Journal of the american leather chemists association, 2017, 112 (10), pp.319-326. ?hal-01646413?
  • Sarah Ameziane-Le Hir, Damien Bourgeois, Christian Basset, Agnès Hagège, Claude Vidaud. Reactivity of U-associated osteopontin with lactoferrin: a one-to-many complex. Metallomics, 2017, 9 (7), pp.865-875. ?10.1039/c7mt00087a?. ?hal-01575210?
  • Maria Betzabeth Espina-Benitez, Lilia Araujo, Avismelsi Prieto, Alberto Navalón, José Vílchez, et al.. Development of a New Microextraction Fiber Combined to On-Line Sample Stacking Capillary Electrophoresis UV Detection for Acidic Drugs Determination in Real Water Samples. International Journal of Environmental Research and Public Health, 2017, 14 (7), pp.Article Number: 739 ?10.3390/ijerph14070739?. ?hal-01583355?
  • Adrien Maniquet, Nicolas Bruyer, Guy Raffin, Franck Baco-Antionali, Claire Demesmay, et al.. Behavior of macroporous vinyl silica and silica monolithic columns in high pressure gas chromatography. Journal of Chromatography A, 2017, 1504, pp.105-111. ?10.1016/j.chroma.2017.05.002?. ?hal-01569429?
  • Maria Betzabeth Espina-Benitez, Jérôme Randon, Claire Demesmay, Vincent Dugas. Development and application of a new in-line coupling of a miniaturized boronate affinity monolithic column with capillary zone electrophoresis for the selective enrichment and analysis of cis-diol-containing compounds. Journal of Chromatography A, 2017, 1494, pp.65-76. ?10.1016/j.chroma.2017.03.014?. ?hal-01519927?
  • A. Martin, C. Margoum, Jérôme Randon, Marina Coquery. Silicone rubber selection for passive sampling of pesticides in water.. Talanta, 2016, 160, pp.306-313. ?10.1016/j.talanta.2016.07.019?. ?hal-01546514?
  • José Néri-Quiroz, Fabrice Canto, Laurent Guillerme, Laurent Couston, Alastair Magnaldo, et al.. Miniaturizing and automation of free acidity measurements for uranium (VI)-HNO3 solutions: Development of a new sequential injection analysis for a sustainable radio-analytical chemistry. Talanta, 2016, 159, pp.330-335. ?10.1016/j.talanta.2016.06.038?. ?hal-01356875?
  • Adrien Maniquet, Nicolas Bruyer, Guy Raffin, Franck Baco-Antoniali, Claire Demesmay, et al.. Behavior of short silica monolithic columns in high pressure gas chromatography.. Journal of Chromatography A, 2016, 1460, pp.153-159. ?10.1016/j.chroma.2016.07.011?. ?hal-01546510?
  • Emmanuelle Cordeau, Carine Arnaudguilhem, Brice Bouyssière, Agnès Hagège, Jean Martinez, et al.. Investigation of elemental mass spectrometry in pharmacology for peptide quantitation at Femtomolar levels. PLoS ONE, 2016, 11 (6), pp.article number: e0157943. ?10.1371/journal.pone.0157943?. ?hal-01356870?
  • Racha El Debs, Pauline Gay, Vincent Dugas, Claire Demesmay. One-pot synthesis of a new high vinyl content hybrid silica monolith dedicated to nanoliquid chromatography. Journal of Separation Science, 2016, 39 (5), pp.842-850. ?10.1002/jssc.201501076?. ?hal-01356863?
  • A. Martin, C. Margoum, Marina Coquery, Jerôme Randon. Combination of sorption properties of polydimethylsiloxane and solid-phase extraction sorbents in a single composite material for passive sampling of polar and apolar pesticides in water. Journal of Separation Science, 2016, 39 (20), pp.3990-3997. ?10.1002/jssc.201600502?. ?hal-01399907?
  • Marielle Crozet, M Peyrillous, E Esbelin, M. H. Garnier, Jérôme Randon. Measurement of C-14 in spent fuel: use of ozone . Journal of Radioanalytical and Nuclear Chemistry, 2016, 307 (1), pp.347-353. ?10.1007/s10967-015-4279-y?. ?hal-01356865?
  • Thi Ngoc Suong Huynh, Claude Vidaud, Agnès Hagège. Investigation of uranium interactions with calcium phosphate-binding proteins using ICP/MS and CE-ICP/MS . Metallomics, 2016, 8 (11), pp.1185-1192 ?10.1039/C6MT00147E?. ?hal-01519885?
  • Racha El Debs, Franck Cadoux, Laurence Bois, Anne Bonhommé, Jérôme Randon, et al.. Synthesis and surface reactivity of vinylized macroporous silica monoliths: one-pot hybrid versus postsynthesis grafting strategies. Langmuir, 2015, 31 (42), pp.11649-11658. ?10.1021/acs.langmuir.5b02681?. ?hal-01234268?
  • Delphine Ach Ach, Stéphanie Briançon, Vincent Dugas, Jocelyne Pelletier, Guy Broze, et al.. Influence of main whey protein components on the mechanism of complex coacervation with Acacia gum. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2015, 481, pp.367-374. ?10.1016/j.colsurfa.2015.06.006?. ?hal-01229834?
  • Philip D. P. Taylor, Danuta Baralkiewicz, Ricardo Bettencourt da Silva, Darinka Brodnjak Voncina, Ewa Bulska, et al.. A summer school where master students learn the skills needed to work in an accredited analytical laboratory. Analytical and Bioanalytical Chemistry, 2015, 407 (23), pp.6899-6907. ?10.1007/s00216-015-8804-1?. ?hal-01229892?
  • Audrey Maréchal, F Jarrosson, Jérôme Randon, Vincent Dugas, Claire Demesmay. In-line coupling of an aptamer based miniaturized monolithic affinity preconcentration unit with capillary electrophoresis and Laser Induced Fluorescence detection. Journal of Chromatography A, 2015, 1406, pp.109-117. ?10.1016/j.chroma.2015.05.073?. ?hal-01186682?
  • Vincent Fauvelle, Tran-Thi Nhu-Trang, Thibaut Feret, Karine Madarassou, Jérôme Randon, et al.. Evaluation of Titanium Dioxide as a Binding Phase for the Passive Sampling of Glyphosate and Aminomethyl Phosphonic Acid in an Aquatic Environment. Analytical Chemistry, 2015, 87 (12), pp.6004-6009. ?10.1021/acs.analchem.5b00194?. ?hal-01186957?
  • Audrey Maréchal, A. Laaniste, Racha El Debs, Vincent Dugas, Claire Demesmay. Versatile ene-thiol photoclick reaction for preparation of multimodal monolithic silica capillary columns. Journal of Chromatography A, 2014, 1365, pp.140-147. ?10.1016/j.chroma.2014.09.017?. ?hal-01073802?
  • A. Laaniste, Audrey Maréchal, Racha El Debs, Jérôme Randon, Vincent Dugas, et al.. "Thiol-ene" photoclick chemistry as a rapid and localizable functionalization pathway for silica capillary monolithic columns.. Journal of Chromatography A, 2014, 1355, pp.296-300. ?10.1016/j.chroma.2014.06.031?. ?hal-01070871?