Interfaces et biocapteurs

Les principales activités du groupe concernent la conception et l’élaboration de microdispositifs et de nanoobjets biofonctionnalisés pour la (bio)détection, le diagnostic médical et les applications thérapeutiques.

Axes de recherche

Pour cela, nous concevons et modifions des surfaces à l’aide de (bio)couches de reconnaissance sensibles, bien adaptées à divers transducteurs optiques ou électrochimiques (ampérométrique, conductométrique, impédancemétrique, etc.).

L’équipe a acquis une solide expérience dans la synthèse et la modification des biomolécules à des fins d’immobilisation sur des microélectrodes à base d’or ou de carbone. Afin d’accroître les performances des dispositifs analytiques (rapidité, sensibilité, robustesse), différentes stratégies sont étudiées par notre groupe, comme notamment l’utilisation de matériaux d’électrode innovants, l’intégration de nanomatériaux conducteurs aux plates-formes de greffage (p. ex., nanoparticules d’or, nanotubes de carbone, graphène, nanofibres), et la substitution de biorécepteurs coûteux et fragiles par des aptamères ou des polymères à empreinte moléculaire. Un nouvel axe de recherche de l’équipe vise à exploiter la technique d’impression 3D de matériaux biosourcés pour l’élaboration rapide, moins coûteuse et/ou plus respectueuse de l’environnement d’électrodes et de dispositifs électrochimiques intégrés.

En utilisant les stratégies originales de modification de surface développées, un certain nombre de biocapteurs à ADN, enzymes, anticorps ont été proposés. Ils ont été appliqués à la détection en temps réel, sensible et sélective de diverses molécules cibles d’intérêt environnemental, alimentaire ou biologique ainsi que des microorganismes. L’un de nos projets actuels est axé sur la détection ultra-sensible des bactéries dans l’eau, les aliments et les fluides biologiques. En ce qui concerne le diagnostic biomédical et les applications thérapeutiques, nous proposons une stratégie originale pour la multi-fonctionnalisation de particules de silice de taille nanométrique (brevet WO/2013/007944). Grâce à cette stratégie, des densités élevées d’ADN, d’aptamères et de protéines peuvent être greffées sur la surface des nanoparticules. Ces conjugués sont d’un grand intérêt pour le développement d’approches innovantes dans les domaines du diagnostic in vitro, de l’imagerie et la thérapie in vivo.

Projets de recherche

ANR 234687 SIENA (2021-2025) : Sensitive peptIde- and apta-assays for on-site detection of bacterial cells and spores in milk and meat samples

Personnels

  • Chercheurs et enseignants-chercheurs

    • Carole CHAIX
    • Latifa FAKRI-BOUCHET
    • Florence LAGARDE
    • Joëlle SAULNIER

  • Soutien à la recherche

    • Carole FARRE

  • Doctorants

    • Eya BENSALEM
    • Mathilde MANCEAU

  • Ingénieur contractuel

    • Abel RANGEL TREJO

  • Autres

    • Samy ANNANE
    • Hussein SLIM

Publications (sources HAL)

Articles dans une revue (121 documents )

  • Ivan Kucherenko, Carole Farre, Gaetan Raimondi, Carole Chaix, Nicole Jaffrezic-Renault, et al.. A novel adenosine triphosphate (ATP) biosensor based on electrospun polymer nanofibers with entrapped hexokinase and glucose oxidase. Applied Nanoscience, 2023, ?10.1007/s13204-023-02861-y?. ?hal-04121224?
  • Vanessa Escobar, Natale Scaramozzino, Jasmina Vidic, Arnaud Buhot, Raphaël Mathey, et al.. Recent Advances on Peptide-Based Biosensors and Electronic Noses for Foodborne Pathogen Detection. Biosensors, 2023, 13, ?10.3390/bios13020258?. ?hal-04307631?
  • Francesco Rizzotto, Majd Khalife, Yanxia Hou, Carole Chaix, Florence Lagarde, et al.. Recent Advances in Electrochemical Biosensors for Food Control. Micromachines, 2023, 14 (7), pp. 1412. ?10.3390/mi14071412?. ?hal-04172926?
  • Meryem Belkilani, Carole Farre, Yves Chevalier, Sylvain Minot, François Bessueille, et al.. Mechanisms of Influenza Virus HA2 Peptide Interaction with Liposomes Studied by Dual-Wavelength MP-SPR. ACS Applied Materials & Interfaces, 2022, ?10.1021/acsami.2c09039?. ?hal-03730479?
  • Arthur Degasperi, Lucie Labied, Carole Farre, Emmanuel Moreau, Matteo Martini, et al.. Probing the protein corona of gold/silica nanoparticles by Taylor dispersion analysis-ICP-MS. Talanta, 2022, 243, pp.123386. ?10.1016/j.talanta.2022.123386?. ?hal-03663936?
  • Ludivine Taiariol, Carole Chaix, Carole Farre, Emmanuel Moreau. Click and Bioorthogonal Chemistry: The Future of Active Targeting of Nanoparticles for Nanomedicines?. Chemical Reviews, 2022, 122 (1), pp.340-384. ?10.1021/acs.chemrev.1c00484?. ?hal-03406814?
  • Nour El Houda Brirmi, Taha Chabbah, Saber Chatti, Frédéric Schiets, Hervé Casabianca, et al.. Effect of the pendent groups on biobased polymers, obtained from click chemistry suitable, for the adsorption of organic pollutants from water. Polymers for Advanced Technologies, In press, ?10.1002/pat.5809?. ?hal-03769693?
  • Meryem Belkilani, Maryam Shokouhi, Carole Farre, Yves Chevalier, Sylvain Minot, et al.. Surface Plasmon Resonance Monitoring of Mono-Rhamnolipid Interaction with Phospholipid-Based Liposomes. Langmuir, 2021, 37 (26), pp.7975-7985. ?10.1021/acs.langmuir.1c00846?. ?hal-03282399?
  • Yannick Bleu, Florent Bourquard, Carole Farre, Carole Chaix, Jules Galipaud, et al.. Boron doped graphene synthesis using pulsed laser deposition and its electrochemical characterization. Diamond and Related Materials, 2021, 115, pp.108382. ?10.1016/j.diamond.2021.108382?. ?hal-03187937?
  • Priya Vizzini, Marisa Manzano, Carole Farre, Thierry Meylheuc, Carole Chaix, et al.. Highly sensitive detection of Campylobacter spp. In chicken meat using a silica nanoparticle enhanced dot blot DNA biosensor. Biosensors and Bioelectronics, 2021, 171, pp.112689. ?10.1016/j.bios.2020.112689?. ?hal-02972078?
  • Amira Nabil, Jose Bernardo, Yue Ma, Mohamed Abouelatta, Ahmed Shaker, et al.. Electrical modeling of tapered TSV including MOS-Field effect and substrate parasitics: Analysis and application. Microelectronics Journal, 2020, 100, pp.104797. ?10.1016/j.mejo.2020.104797?. ?hal-03002039?
  • Elie Akanny, Anne Bonhommé, Carine Commun, Anne Doleans‐jordheim, Carole Farre, et al.. Surface-enhanced Raman spectroscopy using uncoated gold nanoparticles for bacteria discrimination. Journal of Raman Spectroscopy, 2020, 51 (4), pp.619-629. ?10.1002/jrs.5827?. ?hal-02456008?
  • Florence Lagarde. José Manuel Díaz-Cruz, Miquel Esteban, Cristina Ariño: Chemometrics in electroanalysis. Analytical and Bioanalytical Chemistry, 2020, 412, pp.3017-3018. ?10.1007/s00216-020-02522-x?. ?hal-02512058?
  • Mohamed Amine Djebbi, Saber Boubakri, Mohamed Braiek, Nicole Jaffrezic‐renault, Philippe Namour, et al.. Chlorpromazine Electro‐oxidation at BDD Electrode Modified with nZVI Nanoparticles Impregnated NiAl LDH. Electroanalysis, 2020, 32 (6), pp.1186-1197. ?10.1002/elan.201900583?. ?hal-02512044?
  • Yosra Sahraoui, Sana Chaliaa, Abderrazak Maaref, Amor Haddad, François Bessueille, et al.. Synergistic Effect of Polyoxometalate and Single Walled Carbon Nanotubes on Peroxidase‐like Mimics and Highly Sensitive Electrochemical Detection of Hydrogen Peroxide. Electroanalysis, 2020, 32 (4), pp.683-689. ?10.1002/elan.201900415?. ?hal-02464773?
  • Jasmina Vidic, Carole Chaix, Marisa Manzano, Marc Heyndrickx. Food Sensing: Detection of Bacillus cereus Spores in Dairy Products. Biosensors, 2020, 10 (3), pp.15. ?10.3390/bios10030015?. ?hal-02550769?
  • Eleni Sapountzi, Jean-François Chateaux, Florence Lagarde. Combining Electrospinning and Vapor-Phase Polymerization for the Production of Polyacrylonitrile/ Polypyrrole Core-Shell Nanofibers and Glucose Biosensor Application. Frontiers in Chemistry, 2020, 8, pp.678. ?10.3389/fchem.2020.00678?. ?hal-02984012?
  • Ilhem Rassas, Mohamed Braiek, Anne Bonhommé, François Bessueille, Guy Raffin, et al.. Voltammetric glucose biosensor based on glucose oxidase encapsulation in a chitosan-kappa-carrageenan polyelectrolyte complex. Materials Science and Engineering: C, 2019, 95, pp.152-159. ?10.1016/j.msec.2018.10.078?. ?hal-02115795?
  • Xuanying Li, Mengsha Ye, Weiying Zhang, Duo Tan, Nicole Jaffrezic-Renault, et al.. Liquid biopsy of circulating tumor DNA and biosensor applications. Biosensors and Bioelectronics, 2019, 126, pp.596-607. ?10.1016/j.bios.2018.11.037?. ?hal-02115776?
  • Ludivine Vossier, Lionel Valera, Fanny Leon, Stéphanie Roche, Dominique Piquer, et al.. Combining culture and microbead-based immunoassay for the early and generic detection of bacteria in platelet concentrates. Transfusion, 2019, 59 (1), pp.277-286. ?10.1111/trf.15019?. ?hal-01934702?
  • Ilhem Rassas, Mohamed Braiek, Anne Bonhommé, François Bessueille, Guy Raffin, et al.. Highly Sensitive Voltammetric Glucose Biosensor Based on Glucose Oxidase Encapsulated in a Chitosan/Kappa-Carrageenan/Gold Nanoparticle Bionanocomposite. Sensors, 2019, 19 (1), pp.154. ?10.3390/s19010154?. ?hal-02115814?
  • Estelle Lebegue, Carole Farre, Catherine Jose, Joëlle Saulnier, Florence Lagarde, et al.. Biomimetic vesicles for electrochemical sensing. Current Opinion in Electrochemistry, 2018, 12 (12), pp.101-106. ?10.1016/j.coelec.2018.06.005?. ?hal-01928207?
  • Amina Betatache, Florence Lagarde, Nicole Jaffrezic-Renault. Optimization of the surface initiated polymerization of molecular imprinted methacrylate polymer on gold electrode for the detection of testosterone. Journal of New Technology and Materials, 2018, 8 (2), pp.10-15. ?hal-02115862?
  • Hassen Touzi, Yves Chevalier, François Bessueille, Hafedh Ben Ouada, Nicole Jaffrezic-Renault. Detection of dyestuffs with an impedimetric sensor based on Cu2+-methyl-naphthyl cyclen complex functionalized gold electrodes. Sensors and Actuators B: Chemical, 2018, 273, pp.1211-1221. ?10.1016/j.snb.2018.07.011?. ?hal-02115879?
  • Alvaro Garcia-Cruz, Michael J. Lee, Nadia Zine, Monique Sigaud, Pédro Marote, et al.. Biopatterning of antibodies on poly(pyrrole)-nanowires using nanocontact printing: Surface characterization. Materials Science and Engineering: C, 2018, 91, pp.466-474. ?10.1016/j.msec.2018.05.047?. ?hal-01900243?
  • Nicole Jaffrezic-Renault, Christine Mousty. Environmental electrochemical processes: Remediation, energy harvesting and monitoring. Current Opinion in Electrochemistry, 2018, 11, pp.A1-A4. ?10.1016/j.coelec.2018.11.005?. ?hal-02175363?
  • Mohamed Amine Djebbi, Saber Boubakri, Zaineb Bouaziz, Mohamed Slim Elayachi, Philippe Namour, et al.. Extended-release of chlorpromazine intercalated into montmorillonite clays. Microporous and Mesoporous Materials, 2018, 267, pp.43-52. ?10.1016/j.micromeso.2018.03.017?. ?hal-01859896?
  • Saber Boubakri, Mohamed Amine Djebbi, Zaineb Bouaziz, Philippe Namour, Nicole Jaffrezic-Renault, et al.. Removal of two anionic reactive textile dyes by adsorption into MgAl-layered double hydroxide in aqueous solutions. Environmental Science and Pollution Research, 2018, 25 (24), pp.23817-23832. ?10.1007/s11356-018-2391-6?. ?hal-01900248?
  • Xiu Zhang, Jing Cheng, Lei Wu, Yong Mei, Nicole Jaffrezic-Renault, et al.. An overview of an artificial nose system. Talanta, 2018, 184, pp.93-102. ?10.1016/j.talanta.2018.02.113?. ?hal-02115902?
  • Bingqing Shui, Dan Tao, Anca Florea, Jing Cheng, Qin Zhao, et al.. Biosensors for Alzheimer's disease biomarker detection: A review. Biochimie, 2018, 147, pp.13 - 24. ?10.1016/j.biochi.2017.12.015?. ?hal-01770951?
  • Gabriel de Crozals, David Kryza, Gloria Jiménez Sánchez, Stéphane Roux, Doriane Mathé, et al.. Granulocyte Colony-Stimulating Factor Nanocarriers for Stimulation of the Immune System (Part I): Synthesis and Biodistribution Studies. Bioconjugate Chemistry, 2018, 29 (3), pp.795 - 803. ?10.1021/acs.bioconjchem.7b00605?. ?hal-01767382?
  • David Kryza, Gabriel de Crozals, Doriane Mathé, Jacqueline Taleb Sidi-Boumedine, Marc Janier, et al.. Granulocyte-Colony Stimulating Factor Nanocarriers for Stimulation of the Immune System (Part II): Dose-Dependent Biodistribution and In Vivo Antitumor Efficacy in Combination with Rituximab. Bioconjugate Chemistry, 2018, 29 (3), pp.804 - 812. ?10.1021/acs.bioconjchem.7b00606?. ?hal-01767371?
  • Estelle Lebègue, Carole Farre, Catherine Jose, Joëlle Saulnier, Florence Lagarde, et al.. Responsive Polydiacetylene Vesicles for Biosensing Microorganisms. Sensors, 2018, 18 (2), pp.599. ?10.3390/s18020599?. ?hal-01740158?
  • Mohamed Braiek, Mohamed Amine Djebbi, François Chateaux, Anne Bonhommé, Roberto Vargiolu, et al.. A conductometric creatinine biosensor prepared through contact printing of polyvinyl alcohol/polyethyleneimine based enzymatic membrane. Microelectronic Engineering, 2018, 187-188, pp.43 - 49. ?10.1016/j.mee.2017.11.018?. ?hal-01767656?
  • Narjes Kolahchi, Mohamed Braiek, Gholamhossein Ebrahimipour, Seyed Omid Ranaei-Siadat, Florence Lagarde, et al.. Direct detection of phenol using a new bacterial strain-based conductometric biosensor. Journal of Environmental Chemical Engineering, 2018, 6 (1), pp.478-484. ?10.1016/j.jece.2017.12.023?. ?hal-02116197?
  • Lucas Jobin, Catherine Jose, Christophe Pages, Guy Raffin, Xavier Saupin, et al.. Methanogenesis control in bioelectrochemical systems: A carbon footprint reduction assessment. Journal of Environmental Chemical Engineering, 2018, 6 (1), pp.803-810. ?10.1016/j.jece.2017.12.033?. ?hal-01744861?
  • Alvaro Garcia-Cruz, Faiza Nessark, Michael Lee, Nadia Zine, Monique Sigaud, et al.. Efficient fabrication of poly(pyrrole)-nanowires through innovative nanocontact printing, using commercial CD as mold, on flexible thermoplastics substrates: Application for cytokines immunodetection. Sensors and Actuators B: Chemical, 2018, 255, pp.2520-2530. ?10.1016/j.snb.2017.09.057?. ?hal-01646793?
  • Wahid Ben Mefteh, Yves Chevalier, Camelia Bala, Nicole Jaffrezic-Renault. Voltammetric Detection of Copper Ions on a Gold Electrode Modified with a N -methyl-2-naphthyl-cyclam film. Analytical Letters, 2018, 51 (7), pp.971 - 982. ?10.1080/00032719.2017.1368531?. ?hal-01767703?
  • Ali Zazoua, Sarra Bouraoui, Rabiaa Halim, Nawal Khedimallah, Nicole Jaffrezic-Renault. Polyphenolic Natural Products for the Electrochemical Determination of Cadmium. Analytical Letters, 2018, 51 ( 3), pp.359-370. ?10.1080/00032719.2017.1306068?. ?hal-01579599?
  • Bingqing Shui, Dan Tao, Jing Cheng, Yong Mei, Nicole Jaffrezic-Renault, et al.. A novel electrochemical aptamer–antibody sandwich assay for the detection of tau-381 in human serum. Analyst, 2018, 143 (15), pp.3549-3554. ?10.1039/c8an00527c?. ?hal-02115884?
  • Nicole Jaffrezic-Renault, Camelia Bala. Presentation of the MADICA 2016 Special Issue. Analytical Letters, 2018, 51 (3), pp.293 - 295. ?10.1080/00032719.2017.1372463?. ?hal-01692369?
  • Nedjla Zehani, Wilairat Cheewasdtham, Rochdi Kherrat, Nicole Jaffrezic-Renault. Impedimetric Biosensor for the Determination of Phospholipase A 2 Activity in Snake Venom. Analytical Letters, 2018, 51 (03), pp.401-410. ?10.1080/00032719.2017.1312425?. ?hal-01579615?
  • Romaric Bonnet, Carole Farre, Lionel Valera, Ludivine Vossier, Fanny Leon, et al.. Highly labeled methylene blue-ds DNA silica nanoparticles for signal enhancement of immunoassays: application to the sensitive detection of bacteria in human platelet concentrates. Analyst, 2018, 143 (10), pp.2293-2303. ?10.1039/c8an00165k?. ?hal-01859171?
  • Philippe Namour, Lucas Jobin. Electrochemistry, a tool to enhance self-purification in water systems while preventing the emission of noxious gases (greenhouse gases, H 2 S, NH 3 ). Current Opinion in Electrochemistry, 2018, 11, ?10.1016/j.coelec.2018.07.003?. ?hal-01861630?
  • Ali Zazoua, Nawal Khedimallah, Nicole Jaffrezic-Renault. Electrochemical Determination of Cadmium, Lead, and Nickel Using a Polyphenol-Polyvinyl Chloride – Boron-Doped Diamond Electrode. Analytical Letters, 2018, 51 (3), pp.336-347. ?10.1080/00032719.2017.1310879?. ?hal-01580478?
  • Amina Betatache, Jean-François Chateaux, Nicole Jaffrezic-Renault. Conception and Characterization of Moleculary Imprinted Polymers Nanofibers of Poly (Ethylene-Co-vinyl Alcohol) and Their Use as Membrane in Electrochemical Sensor for Creatinine Detection. Journal of New Technology and Materials, 2018, 8 (1), pp.68-73. ?10.12816/0048926?. ?hal-02115920?
  • Latifa Fakri-Bouchet, Mohammed Zahraoui. Implantable Microcoil for In-vivo Magnetic Resonance Spectroscopy. International Journal of Biosensors & Bioelectronics, 2017, 3 (2), pp.237 - 240. ?10.15406/ijbsbe.2017.03.00056?. ?hal-01934560?
  • Zaineb Bouaziz, Mohamed Amine Djebbi, Laurence Soussan, Jean-Marc Janot, Abdesslem Ben Haj Amara, et al.. Adsorption of nisin into layered double hydroxide nanohybrids and in-vitro controlled release. Materials Science and Engineering: C, 2017, 76, pp.673 - 683. ?10.1016/j.msec.2017.03.143?. ?hal-01675173?
  • Hana Fourou, Mohamed Braiek, Anne Bonhommé, Florence Lagarde, Ali Zazoua, et al.. Voltammetric Sensor Based on a Double-Layered Molecularly Imprinted Polymer for Testosterone. Analytical Letters, 2017, 51 (3), pp.312-322. ?10.1080/00032719.2017.1298118?. ?hal-02116237?
  • Mihaela Tertiş, Anca Florea, Alina Adumitrăchioaie, Andreea Cernat, Diana Bogdan, et al.. Detection of Dopamine by a Biomimetic Electrochemical Sensor Based on Polythioaniline-Bridged Gold Nanoparticles. ChemPlusChem, 2017, 82 (4), pp.561-569. ?10.1002/cplu.201600539?. ?hal-01551858?
  • Asma Saadaoui, Sanglar Corinne, Raouf Medimagh, Anne Bonhommé, Robert Baudot, et al.. New biosourced chiral molecularly imprinted polymer: Synthesis, characterization, and evaluation of the recognition capacity of methyltestosterone. Journal of Molecular Recognition, 2017, 30 (4), pp.e2594. ?10.1002/jmr.2594?. ?hal-01518965?
  • Oleksandr O Soldatkin, K. V. Stepurska, V. M. Arkhypova, A.P. Soldatkin, A. V. El'Skaya, et al.. Conductometric enzyme biosensor for patulin determination. Sensors and Actuators B: Chemical, 2017, 239, pp.1010-1015. ?10.1016/j.snb.2016.08.121?. ?hal-01519020?
  • Jasmina Vidic, Marisa Manzano, Chung-Ming Chang, Nicole Jaffrezic-Renault. Advanced biosensors for detection of pathogens related to livestock and poultry. Veterinary Research, 2017, 48 (1), pp.11. ?10.1186/s13567-017-0418-5?. ?hal-01499743?
  • Eleni Sapountzi, Mohamed Braiek, Francis Vocanson, Jean-François Chateaux, Nicole Jaffrezic-Renault, et al.. Gold nanoparticles assembly on electrospun poly(vinylalcohol) /poly(ethyleneimine)/glucose oxidase nanofibers for ultrasensitive electrochemical glucose biosensing . Sensors and Actuators B: Chemical, 2017, 238, pp.392-401. ?10.1016/j.snb.2016.07.062?. ?ujm-01514982?
  • Eleni Sapountzi, Mohamed Braiek, Jean-François Chateaux, Nicole Jaffrezic-Renault, Florence Lagarde. Recent Advances in Electrospun Nanofiber Interfaces for Biosensing Devices. Sensors, 2017, 17 (8), pp.1887. ?10.3390/s17081887?. ?hal-01579587?
  • Zhenzhong Guo, Anca Florea, Mengjuan Jiang, Yong Mei, Weiying Zhang, et al.. Molecularly Imprinted Polymer/Metal Organic Framework Based Chemical Sensors. Coatings, 2016, 6 (4), pp. Article Number: 42 ?10.3390/coatings6040042?. ?hal-01546551?
  • Mohamed Amine Djebbi, Alae Elabed, Zaineb Bouaziz, Moulay Sadiki, Soumya Elabed, et al.. Delivery system for berberine chloride based on the nanocarrier ZnAl-layered double hydroxide: Physicochemical characterization, release behavior and evaluation of anti-bacterial potential. International Journal of Pharmaceutics, 2016, 515 (1-2), pp.422-430. ?10.1016/j.ijpharm.2016.09.089?. ?hal-02116971?
  • Mohamed Braiek, Mohamed Amine Djebbi, Jean-François Chateaux, Nicole Jaffrezic-Renault. A conductometric sensor for potassium detection in whole blood. Sensors and Actuators B: Chemical, 2016, 235, pp.27-32. ?10.1016/j.snb.2016.05.050?. ?hal-01546540?
  • Lotfi Mhamdi, Nejib Mhamdi, Naceur Mhamdi, Philippe Lejeune, Nicole Jaffrezic-Renault, et al.. Effect of a static magnetic field on Escherichia coli adhesion and orientation. Canadian Journal of Microbiology, 2016, 62 (11), pp.944-952. ?10.1139/cjm-2015-0839?. ?hal-01546555?
  • Mohamed Djebbi, Mohamed Braiek, Philippe Namour, Abdesslem Ben Haj Amara, Nicole Jaffrezic-Renault. Layered double hydroxide materials coated carbon electrode: New challenge to future electrochemical power devices. Applied Surface Science, 2016, 386, pp.352-363. ?10.1016/j.apsusc.2016.06.032?. ?hal-01546546?
  • Yosra Sahraoui, Sana Chaalia, Abderrazak Maaref, Amor Haddad, François Bessueille, et al.. Mediator enhanced glucose detection using organic?inorganic hybrid supramolecular assembly on gold electrodes. Journal of Electroanalytical Chemistry, 2016, 781, pp.190-197. ?10.1016/j.jelechem.2016.09.018?. ?hal-01546557?
  • Madiha Bougrini, Abdoullatif Baraket, Talha Jamshaid, Abdelhamid Elaissari, Joan Bausells, et al.. Development of a novel capacitance electrochemical biosensor based on silicon nitride for ochratoxin A detection. Sensors and Actuators B: Chemical, 2016, 234, pp.446-452. ?10.1016/j.snb.2016.03.166?. ?hal-01546538?
  • Mohamed Braiek, Yi Yang, Carole Farre, Carole Chaix, François Bessueille, et al.. Boron-doped Diamond Electrodes Modified with Fe 3 O 4 @Au Magnetic Nanocomposites as Sensitive Platform for Detection of a Cancer Biomarker, Interleukin-8.. Electroanalysis, 2016, 28 (8), pp.1810-1816. ?10.1002/elan.201600060?. ?hal-01546541?
  • Gabriel de Crozals, Romaric Bonnet, Carole Farre, Carole Chaix. Nanoparticles with multiple properties for biomedical applications: A strategic guide. Nano Today, 2016, 11 (4), pp.435-463. ?10.1016/j.nantod.2016.07.002?. ?hal-01546542?
  • Alvaro Garcia-Cruz, Michael Lee, Pedro Marote, Nadia Zine, Monique Sigaud, et al.. Large area in situ fabrication of poly(pyrrole)-nanowires on flexible thermoplastic films using nanocontact printing . Materials Research Express, 2016, 3 (8), pp. Article Number: 085018 ?10.1088/2053-1591/3/8/085018?. ?hal-01544850?
  • Hana Fourou, Ali Zazoua, Mohamed Braiek, Nicole Jaffrezic-Renault. An enzyme biosensor based on beta-galactosidase inhibition for electrochemical detection of cadmium (II) and chromium (VI). International Journal of Environmental Analytical Chemistry, 2016, 96 (9), pp.872-885. ?10.1080/03067319.2016.1209659?. ?hal-01546547?
  • Mohamed Amine Djebbi, Zaineb Bouaziz, Alae Elabed, Moulay Sadiki, Soumya Elabed, et al.. Preparation and optimization of a drug delivery system based on berberine chloride-immobilized MgAl hydrotalcite. International Journal of Pharmaceutics, 2016, 506 (1-2), pp.438-448. ?10.1016/j.ijpharm.2016.04.048?. ?hal-01363673?
  • C. Maddi, Florent Bourquard, T Tite, A.-S. Loir, C. Donnet, et al.. Structure, electrochemical properties and functionalization of amorphous CN films deposited by femtosecond pulsed laser ablation. Diamond and Related Materials, 2016, DIAMOND AND RELATED MATERIALS, 65, pp.17-25. ?10.1016/j.diamond.2016.01.001?. ?hal-01363692?
  • Lucian Rotariu, Florence Lagarde, Nicole Jaffrezic-Renault, Camelia Bala. Electrochemical biosensors for fast detection of food contaminants trends and perspective. Trends in Analytical Chemistry, 2016, 79, pp.80-87. ?10.1016/j.trac.2015.12.017?. ?hal-01363674?
  • Ivan S Kucherenko, D. Yu. Kucherenko, Oleksandr O Soldatkin, Florence Lagarde, S.V. Dzyadevych, et al.. A novel conductometric biosensor based on hexokinase for determination of adenosine triphosphate. Talanta, 2016, 150, pp.469-475 ?10.1016/j.talanta.2015.12.069?. ?hal-01363675?
  • Ali Houmed Adabo, Rabah Zeggari, Nasser Mohamed Said, Rana Bazzi, Céline Elie-Caille, et al.. Enhanced chemiluminescence-based detection on gold substrate after electrografting of diazonium precursor-coated gold nanoparticles. Journal of Colloid and Interface Science, 2016, 467, pp.271-279. ?10.1016/j.jcis.2016.01.030?. ?hal-01363650?
  • C. Ben Ali Hassine, H Barhoumi, A Maaref, Nicole Jaffrezic-Renault. Copper(II)-Selective Sensor Based on Modified Glassy Carbon Electrode by Aurintricarboxylic Acid Ammonium Salt (ATA). Sensor letters, 2016, 14 (4), pp.376-381. ?10.1166/sl.2016.3618?. ?hal-01363670?
  • Wahid Ben Mefteh, Hassen Touzi, Yves Chevalier, Rafik Kalfat, Nicole Jaffrezic-Renault. Effect of pH on the detection of metal ions using a ISFET sensor modified with a polysiloxane film substituted by naphtyl-cyclam. Sensor letters, 2016, 14 (3), pp.246-252. ?10.1166/sl.2016.3674?. ?hal-01363669?
  • Mohamed Amine Djebbi, Mohamed Braiek, Slah Hidouri, Philippe Namour, Nicole Jaffrezic-Renault, et al.. Novel biohybrids of layered double hydroxide and lactate dehydrogenase enzyme: Synthesis, characterization and catalytic activity studies. Journal of Molecular Structure, 2016, 1105, pp.381-388. ?10.1016/j.molstruc.2015.10.065?. ?hal-01251196?
  • Philippe Fortgang, Teddy Tite, Vincent Barnier, Nedjla Zehani, Chiranjeevi Maddi, et al.. Robust Electrografting on Self-Organized 3D Graphene Electrodes. ACS Applied Materials & Interfaces, 2016, 8 (Issue : 2), pp.1424-1433. ?10.1021/acsami.5b10647?. ?emse-01496461?
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