Image de Sophie AYCIRIEX

Sophie AYCIRIEX

Enseignant-chercheur

Numéro ORCID : 0000-0003-4813-5900


423 565 (Standard + 33 [0]437 423 535)
B2B05

Rattachements

Analyses biologiques par spectrométrie de masse

IHU - SPATIAL MULTI-OMICS

Multi-dimensions pour les mélanges complexes (MDMC) (responsable)

Publications (source HAL)

Articles dans une revue (40 documents )

    • -Natacha Koenig, Patrice Baa-Puyoulet, Amélie Lafont, Isis Lorenzo-Colina, Vincent Navratil, et al.. Proteogenomic reconstruction of organ-specific metabolic networks in an environmental sentinel species, the amphipod Gammarus fossarum. Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics, 2024, 52, pp.101323.
      • 10.1016/j.cbd.2024.101323 hal-04704294
    • -Patricia Laquel, Sophie Ayciriex, François Doignon, Nadine Camougrand, Louise Fougère, et al.. Mlg1, a yeast acyltransferase located in ER membranes associated with mitochondria ( MAMs ), is involved in de novo synthesis and remodelling of phospholipids. FEBS Journal, 2024, 291 (12), pp.2683-2702.
      • 10.1111/febs.17068 hal-04431763
    • -Thomas Alexandre Brunet, Yohann Clément, Valentina Calabrese, Jérôme Lemoine, Olivier Geffard, et al.. Concomitant investigation of crustacean amphipods lipidome and metabolome during the molting cycle by Zeno SWATH data-independent acquisition coupled with electron activated dissociation and machine learning. Analytica Chimica Acta, 2024, 1304, pp.342533.
      • 10.1016/j.aca.2024.342533 hal-04535105
    • -Tingting Fu, Valentina Calabrese, Anabelle Espeyte, Sarah Bancel, Hervé Quéau, et al.. ToF-SIMS imaging shows specific lipophilic vitamin alterations in chronic reprotoxicity caused by the emerging contaminant Pravastatin in Gammarus fossarum.. Aquatic Toxicology, 2024, 271, pp.106935.
      • 10.1016/j.aquatox.2024.106935 hal-04565127
    • -Valentina Calabrese, Thomas Alexandre Brunet, Davide Degli-Esposti, Arnaud Chaumot, Olivier Geffard, et al.. Electron-activated dissociation (EAD) for the complementary annotation of metabolites and lipids through data-dependent acquisition analysis and feature-based molecular networking, applied to the sentinel amphipod Gammarus fossarum. Analytical and Bioanalytical Chemistry, 2024, 416 (12), pp.2893-2911.
      • 10.1007/s00216-024-05232-w hal-04507595
    • -Mukesh Kumar, Canan Has, Khanh Lam-Kamath, Sophie Ayciriex, Deepshe Dewett, et al.. Lipidome Unsaturation Affects the Morphology and Proteome of the Drosophila Eye. Journal of Proteome Research, 2024,
      • 10.1021/acs.jproteome.3c00570 hal-04519027
    • -Guillaume Rossignol, Xavier Muller, Thomas Alexandre Brunet, Valeska Bidault, Valerie Hervieu, et al.. Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model of ischemia-reperfusion injury. Scientific Reports, 2024, 14 (1), pp.2384.
      • 10.1038/s41598-024-52504-7 hal-04425302
    • -Guillaume Rossignol, Xavier Muller, Thomas Alexandre Brunet, Valeska Bidault, Valerie Hervieu, et al.. Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model of ischemia-reperfusion injury. Scientific Reports, 2024, 14 (1), pp.2384.
      • 10.1038/s41598-024-52504-7 hal-04502857
    • -Vijaykumar Patra, Natalie Bordag, Yohann Clément, Harald Köfeler, Jean-Francois Nicolas, et al.. Ultraviolet exposure regulates skin metabolome based on the microbiome. Scientific Reports, 2023, 13 (1), pp.7207.
      • 10.1038/s41598-023-34073-3 hal-04091111
    • -Mukesh Kumar, Canan Has, Khanh Lam-Kamath, Sophie Ayciriex, Deepshe Dewett, et al.. Eye proteome of Drosophila melanogaster. Proteomics, 2023, 24 (10),
      • 10.1002/pmic.202300330 hal-04769955
    • -Maxime Leprêtre, Arnaud Chaumot, Rayan Aboud, Nicolas Delorme, Anabelle Espeyte, et al.. Dynamic Multiple Reaction Monitoring of amphipod Gammarus fossarum caeca expands molecular information for understanding the impact of contaminants. Science of the Total Environment, 2023, 893, pp.164875.
      • 10.1016/j.scitotenv.2023.164875 hal-04358369
    • -Thomas Alexandre Brunet, Sophie Ayciriex, Delphine Arquier, Jérôme Lemoine, Jérôme Randon, et al.. Scout triggered multiple reaction monitoring mass spectrometry for the rapid transfer of large multiplexed targeted methods in metabolomics.. Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2023, 1228, pp.123849.
      • 10.1016/j.jchromb.2023.123849 hal-04216213
    • -Julien Faugere, Thomas Alexandre Brunet, Yohann Clément, Anabelle Espeyte, Olivier Geffard, et al.. Development of a multi-omics extraction method for ecotoxicology: investigation of the reproductive cycle of Gammarus fossarum. Talanta, 2023, 253, pp.123806.
      • 10.1016/j.talanta.2022.123806 hal-03773623
    • -Valentina Calabrese, Arnaud Salvador, Yohann Clément, Thomas Alexandre Brunet, Anabelle Espeyte, et al.. Challenges and perspectives in MS-based omics approaches for ecotoxicology studies: An insight on Gammarids sentinel amphipods. Frontiers in Analytical Science, 2023, 3, pp.1118494.
      • 10.3389/frans.2023.1118494 hal-03986050
    • -Aurélien Scalabre, Yohann Clément, Florence Guillière, Sophie Ayciriex, Ségolène Gaillard, et al.. Early detection of ureteropelvic junction obstruction in neonates with prenatal diagnosis of renal pelvis dilatation using 1H NMR urinary metabolomics. Scientific Reports, 2022, 12 (1), pp.13406.
      • 10.1038/s41598-022-17664-4 hal-03745903
    • -Maxime Leprêtre, Olivier Geffard, Anabelle Espeyte, Julien Faugere, Sophie Ayciriex, et al.. Multiple reaction monitoring mass spectrometry for the discovery of environmentally modulated proteins in an aquatic invertebrate sentinel species, Gammarus fossarum. Environmental Pollution, 2022, 315, pp.120393.
      • 10.1016/j.envpol.2022.120393
    • -Mukesh Kumar, Canan Has, Khanh Lam-Kamath, Sophie Ayciriex, Deepshe Dewett, et al.. Vitamin A Deficiency Alters the Phototransduction Machinery and Distinct Non-Vision-Specific Pathways in the Drosophila Eye Proteome. Biomolecules, 2022, 12 (8), pp.1083.
      • 10.3390/biom12081083 hal-03751366
    • -Kyle Thompson, Lucas Bianchi, Francesca Rastelli, Florence Piron-Prunier, Sophie Ayciriex, et al.. Biallelic variants in TAMM41 are associated with low muscle cardiolipin levels, leading to neonatal mitochondrial disease. Human Genetics and Genomics Advances, 2022, 3 (2), pp.100097.
      • 10.1016/j.xhgg.2022.100097 hal-03675447
    • -Tingting Fu, Oskar Knittelfelder, Yohann Clément, Eric Testet, Nicolas Elie, et al.. Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in Gammarus fossarum lipid composition. iScience, 2021, 24 (2), pp.1-44.
      • 10.1016/j.isci.2021.102115 hal-03134038
    • -Ivano Di Meo, Chiara Cavestro, Silvia Pedretti, Tingting Fu, Simona Ligorio, et al.. Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model. International Journal of Molecular Sciences, 2020, 21 (24), pp.9707.
      • 10.3390/ijms21249707 hal-03116877
    • -Tingting Fu, Janina Oetjen, Manuel Chapelle, Alexandre Verdu, Matthias Szesny, et al.. In situ isobaric lipid mapping by MALDI-ion mobility separation-mass spectrometry imaging. Journal of Mass Spectrometry, 2020, 55 (9), pp.e4531.
      • 10.1002/jms.4531 hal-03113280
    • -Julien Faugère, Duarte Gouveia, Sophie Ayciriex, Arnaud Chaumot, Christine Almunia, et al.. High-multiplexed monitoring of protein biomarkers in the sentinel Gammarus fossarum by targeted scout-MRM assay, a new vision for ecotoxicoproteomics. Journal of Proteomics, 2020, 226, pp.103901.
      • 10.1016/j.jprot.2020.103901 hal-02903090
    • -Arnaud Salvador, Romain Carrière, Sophie Ayciriex, Christelle Margoum, Yves Leblanc, et al.. Scout-multiple reaction monitoring: A liquid chromatography tandem mass spectrometry approach for multi-residue pesticide analysis without time scheduling. Journal of Chromatography A, 2020, 1621, pp.461046.
      • 10.1016/j.chroma.2020.461046 hal-02771252
    • -Sophie Ayciriex, Romain Carrière, Chloé Bardet, Yves J. C. Le Blanc, Arnaud Salvador, et al.. Streamlined Development of Targeted Mass Spectrometry‐Based Method Combining Scout‐MRM and a Web‐Based Tool Indexed with Scout Peptides. Proteomics, 2020, pp.1900254.
      • 10.1002/pmic.201900254 hal-02436928
    • -Aurore Charnot, Duarte Gouveia, Sophie Ayciriex, Jérôme Lemoine, J. Armengaud, et al.. On-Line Solid Phase Extraction Liquid Chromatography-Mass Spectrometry Method for Multiplexed Proteins Quantitation in an Ecotoxicology Test Specie: Gammarus fossarum. Journal of Applied Bioanalysis, 2018, 4 (3), pp.81-101.
      • 10.17145/jab.18.012 hal-01860702
    • -Sophie Ayciriex, Fathia Djelti, Sandro Alves, Anne Regazzetti, Mathieu Gaudin, et al.. Neuronal Cholesterol Accumulation Induced by Cyp46a1 Down-Regulation in Mouse Hippocampus Disrupts Brain Lipid Homeostasis. Frontiers in Molecular Neuroscience, 2017, 10,
      • 10.3389/fnmol.2017.00211 hal-03220550
    • -Blandine Rougemont, Sebastien B Gallo, Sophie Ayciriex, Romain Carrière, Hubert Hondermarck, et al.. Scout-MRM: Multiplexed Targeted Mass Spectrometry-Based Assay without Retention Time Scheduling Exemplified by Dickeya dadantii Proteomic Analysis during Plant Infection. Analytical Chemistry, 2017, 89 (3), pp.1421-1426
      • 10.1021/acs.analchem.6b03201 hal-01518912
    • -Sophie Ayciriex, H. Gerber, M. Osuna, M. Chami, H. Stahlberg, et al.. The lipidome associated with the gamma-secretase complex is required for its integrity and activity. Biochemical Journal, 2016, 473 (3), pp.321 - 334.
      • 10.1042/BJ20150448 hal-01779038
    • -Sophie Ayciriex, Marie-Anne Burlot, Jérome Braudeau, Kristin Michaelsen-Preusse, Brigitte Potier, et al.. Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology. Human Molecular Genetics, 2015, 24 (21), pp.5965 - 5976.
      • 10.1093/hmg/ddv268 hal-01779042
    • -Sophie Ayciriex, Fathia Djelti, Jérome Braudeau, Eloise Hudry, Marc Dhenain, et al.. CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer’s disease. Brain - A Journal of Neurology , 2015, 138 (8), pp.2383 - 2398.
      • 10.1093/brain/awv166 hal-01779044
    • -Michael Habeck, Haim Haviv, Adriana Katz, Einat Kapri-Pardes, Sophie Ayciriex, et al.. Stimulation, Inhibition, or Stabilization of Na,K-ATPase Caused by Specific Lipid Interactions at Distinct Sites. Journal of Biological Chemistry, 2015, 290 (8), pp.4829 - 4842.
      • 10.1074/jbc.M114.611384 hal-01779047
    • -Jonathan Rodenfels, Oksana Lavrynenko, Sophie Ayciriex, Julio Sampaio, Maria Carvalho, et al.. Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development. Genes and Development, 2014, 28 (23), pp.2636 - 2651.
      • 10.1101/gad.249763.114 hal-01779049
    • -Mathieu Gaudin, Mai Panchal, Sophie Ayciriex, Erwan Werner, Alain Brunelle, et al.. Ultra performance liquid chromatography - mass spectrometry studies of formalin-induced alterations of human brain lipidome. Journal of Mass Spectrometry, 2014, 49 (10), pp.1035 - 1042.
      • 10.1002/jms.3424 hal-01779050
    • -Mai Panchal, Mathieu Gaudin, Adina Lazar, Elisa Salvati, Isabelle Rivals, et al.. Ceramides and sphingomyelinases in senile plaques. Neurobiology of Disease, 2014, 65, pp.193 - 201.
      • 10.1016/j.nbd.2014.01.010 hal-01779051
    • -Maï Panchal, Mathieu Gaudin, Adina Lazar, Elisa Salvati, Isabelle Rivals, et al.. Ceramides and sphingomyelinases in senile plaques. Neurobiology of Disease, 2014, 65, pp.193-201.
      • 10.1016/j.nbd.2014.01.010 hal-03572624
    • -Corinne Bure, Sophie Ayciriex, Eric Testet, Jean-Marie Schmitter. A single run LC-MS/MS method for phospholipidomics. Analytical and Bioanalytical Chemistry, 2013, 405 (1), pp.203 - 213.
      • 10.1007/s00216-012-6466-9 hal-01779053
    • -Sophie Ayciriex, Marina Le Guédard, Nadine Camougrand, Gisèle Velours, Mario Schoene, et al.. YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with liquid droplets and involved in TAG homeostasis. Molecular Biology of the Cell, 2012, 23 (2), pp.233-400.
      • 10.1091/mbc.e11-07-0650 hal-00702263
    • -S. Ayciriex, D. Touboul, A. Brunelle, O. Laprévote. Time-of-flight secondary ion mass spectrometry: a novel tool for lipid imaging. Clin Lipidol, 2011, 6 (4), pp.437-445.
      • 10.2217/CLP.11.31 hal-00673010
    • -Marina Le Guédard, Jean-Jacques Bessoule, Valérie Wattelet-Boyer, Sophie Ayciriex, Gisèle Velours, et al.. PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast. FEBS Journal, 2009, 276 (21), pp.6412-6424.
      • 10.1111/j.1742-4658.2009.07355.x hal-04535112
41