Image de Adriana MIELE

Adriana MIELE

Enseignant-chercheur

Numéro ORCID : 0000-0002-4637-2606


423 607 (Standard + 33 [0]437 423 535)
B0B03

Rattachements

Approches Théoriques et Expérimentales des Interactions Moléculaires (responsable)

Biophysique des systèmes complexes

Publications (source HAL)

Articles dans une revue (24 documents )

    • -Mauro Giorgi, Adriana Erica Miele, Silvia Cardarelli, Alessandra Giorgi, Mara Massimi, et al.. Structural Characterization of Murine Phosphodiesterase 5 Isoforms and Involvement of Cysteine Residues in Supramolecular Assembly. International Journal of Molecular Sciences, 2023, 24 (2), pp.1108.
      • 10.3390/ijms24021108 hal-03989112
    • -Štěpánka Nedvědová, Davide de Stefano, Olivier Walker, Maggy Hologne, Adriana Erica Miele. Revisiting Schistosoma mansoni Micro-Exon Gene (MEG) Protein Family: A Tour into Conserved Motifs and Annotation. Biomolecules, 2023, 13 (9), pp.1275.
      • 10.3390/biom13091275 hal-04189192
    • -Cecilia Rocchi, Camille Louvat, Adriana Miele, Julien Batisse, Christophe Guillon, et al.. The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding. International Journal of Molecular Sciences, 2022, 23 (22), pp.13742.
      • 10.3390/ijms232213742 hal-03434126
    • -Silvia Cardarelli, Adriana Erica Miele, Federica Campolo, Mara Massimi, Patrizia Mancini, et al.. Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms. International Journal of Molecular Sciences, 2022, 23 (15), pp.8587.
      • 10.3390/ijms23158587 hal-04004278
    • -Adriana Miele, Laura Cervoni, Aline Le Roy, Antimo Cutone, Giovanni Musci, et al.. Biophysical characterization of the complex between the iron-responsive transcription factor Fep1 and DNA. European Biophysics Journal, 2021,
      • 10.1007/s00249-020-01489-y
    • -Frank Gondelaud, Mathilde Bouakil, Aurélien Le Fèvre, Adriana E. Miele, Fabien Chirot, et al.. Extended disorder at the cell surface: The conformational landscape of the ectodomains of syndecans. Matrix Biology Plus, 2021, 12, pp.100081.
      • 10.1016/j.mbplus.2021.100081 hal-04998857
    • -Sylvie Ricard-Blum, Adriana E Miele. Omic approaches to decipher the molecular mechanisms of fibrosis, and design new anti-fibrotic strategies. Seminars in Cell and Developmental Biology, 2020, 101, pp.161-169.
      • 10.1016/j.semcdb.2019.12.009 hal-04998726
    • -Adriana E Miele, Sofiane Badaoui, Lorenzo Maugliani, Romain Salza, Giovanna Boumis, et al.. A comparative analysis of secreted protein disulfide isomerases from the tropical co-endemic parasites Schistosoma mansoni and Leishmania major. Scientific Reports, 2019, 9 ((1)), pp.9568.
      • 10.1038/s41598-019-45709-8 hal-04963995
    • -Sylvain Vallet, Adriana Miele, Urszula Uciechowska-Kaczmarzyk, Adam Liwo, Bertrand Duclos, et al.. Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners. Scientific Reports, 2018, 8 (1), pp.122-149.
      • 10.1038/s41598-018-30190-6 hal-02109680
    • -Silvia Cardarelli, Adriana Erica Miele, Carlotta Zamparelli, Stefano Biagioni, Fabio Naro, et al.. The oligomeric assembly of the phosphodiesterase-5 is a mixture of dimers and tetramers: A putative role in the regulation of function. Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (10), pp.2183-2190.
      • 10.1016/j.bbagen.2018.07.010 hal-02109690
    • -Ilaria Silvestri, Haining Lyu, Francesca Fata, Giovanna Boumis, Adriana Miele, et al.. Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry. ACS Chemical Biology, 2018, 13 (8), pp.2190-2202.
      • 10.1021/acschembio.8b00349 hal-02109710
    • -Antimo Cutone, Barry D. Howes, Adriana E. Miele, Rossella Miele, Alessandra Giorgi, et al.. Pichia pastoris Fep1 is a [2Fe-2S] protein with a Zn finger that displays an unusual oxygen-dependent role in cluster binding. Scientific Reports, 2016, 6 (31872), pp.1-12.
      • 10.1038/srep31872 hal-01541882
    • -F. Angelucci, F. Saccoccia, M. Ardini, G. Boumis, M. Brunori, et al.. Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis.. Journal of Molecular Biology, 2013, 425 (22), pp.4556-68.
      • 10.1016/j.jmb.2013.09.002 pasteur-01022642
    • -Adriana Erica Miele, Andrea Bellelli, Maurizio Brunori. Hemoglobin allostery: new views on old players.. Journal of Molecular Biology, 2013, 425 (9), pp.1515-26.
      • 10.1016/j.jmb.2012.12.018 pasteur-01025328
    • -Giovanna Boumis, Giorgio Giardina, Francesco Angelucci, Andrea Bellelli, Maurizio Brunori, et al.. Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target.. Biochemical and Biophysical Research Communications, 2012, 425 (4), pp.806-11.
      • 10.1016/j.bbrc.2012.07.156 pasteur-00952042
    • -Fulvio Saccoccia, Patrizio Di Micco, Giovanna Boumis, Maurizio Brunori, Ilias Koutris, et al.. Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin.. Structure, 2012, 20 (3), pp.429-39.
      • 10.1016/j.str.2012.01.004 pasteur-00952065
    • -Fulvio Saccoccia, Francesco Angelucci, Giovanna Boumis, Maurizio Brunori, Adriana E Miele, et al.. On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases.. Journal of Inorganic Biochemistry, 2012, 108, pp.105-11.
      • 10.1016/j.jinorgbio.2011.11.005 pasteur-00952028
    • -Giovanna Boumis, Francesco Angelucci, Andrea Bellelli, Maurizio Brunori, Daniela Dimastrogiovanni, et al.. Structural and functional characterization of Schistosoma mansoni Thioredoxin.. Protein Science, 2011, 20 (6), pp.1069-76.
      • 10.1002/pro.634 pasteur-00975317
    • -Carmelinda Savino, Adriana E Miele, Federica Draghi, Kenneth A Johnson, Giuliano Sciara, et al.. Pattern of cavities in globins: the case of human hemoglobin.. Biopolymers, 2009, 91 (12), pp.1097-1107.
      • 10.1002/bip.21201 hal-01617675
    • -Carmelinda Savino, Linda C Montemiglio, Giuliano Sciara, Adriana E Miele, Steven G Kendrew, et al.. Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate.. Journal of Biological Chemistry, 2009, 284 (42), pp.29170-9.
      • 10.1074/jbc.M109.003590 hal-01617673
    • -Carmelinda Savino, Giuliano Sciara, Adriana E Miele, Steven G Kendrew, Beatrice Vallone. Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of C-12 hydroxylase EryK from Saccharopolyspora erythraea.. Protein and Peptide Letters, 2008, 15 (10), pp.1138-1141.
      • 10.2174/092986608786071201 hal-01617667
    • -Dominique Bourgeois, Beatrice Vallone, Friedrich Schotte, Alessandro Arcovito, Adriana E Miele, et al.. Complex landscape of protein structural dynamics unveiled by nanosecond Laue crystallography.. Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (15), pp.8704-9.
      • 10.1073/pnas.1430900100 hal-01595186
    • -Giuliano Sciara, Steven G Kendrew, Adriana E Miele, Neil G Marsh, Luca Federici, et al.. The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.. EMBO Journal, 2003, 22 (2), pp.205-15.
      • 10.1093/emboj/cdg031 hal-01595326
    • -Adriana E Miele, Luca Federici, Giuliano Sciara, Federica Draghi, Maurizio Brunori, et al.. Analysis of the effect of microgravity on protein crystal quality: the case of a myoglobin triple mutant.. Acta crystallographica Section D : Structural biology [1993-..], 2003, 59 (6), pp.982-928.
      • hal-01595187
25